COVID-19: False negatives on test raise questions about accuracy

New research is raising more questions about tests used around the U.S. to diagnose Covid-19 patients, with some of the tests producing a surprisingly high rate of false negatives that incorrectly show a person isn’t infected.One study released Wednesday examining an Abbott Laboratories test that’s used at the White House to get rapid diagnoses indicated it may miss as many as half of positive cases. A second peer-reviewed study released hours later suggested that results for another type of widely used diagnostic test are particularly unreliable early on in an infection.The first study found that Abbott’s ID NOW machine missed at least one-third of positive cases detected with a rival test, and as many as 48% when using the currently recommended dry nasal swabs, according to the report on BioRxiv, a server where researchers post early work before it has been reviewed by other scientists.Abbott immediately disputed the results, which came from researchers at New York University, and said that they didn’t use the test as intended. The company said its data showed a false-negative rate of 0.02%.The second analysis, published in the Annals of Internal Medicine and authored by Johns Hopkins researchers, analyzed seven previously-published studies evaluating 1,330 patient… Read full this story

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