A young couple was killed in a wrong-way crash in Queens early Saturday when their motorcycle slammed into a van, police said. The 22-year-old motorcyclist — with his 20-year-old girlfriend sitting behind him — was whizzing down 43rd Avenue near 38th Street in Sunnyside against the flow of traffic around 3:30 a.m., cops said. Suddenly, he crashed into a red Ford E250 van heading north on the one-way street. The couple was catapulted onto the street, and suffered severe body trauma, cops said. They were rushed to Elmhurst Hospital Center, where both were pronounced dead. The 27-year-old van driver remained on scene and refused medical attention. No arrests were made, and the victims’ names have not been released pending family notification.